Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955340 | 0.91 | THRA (0.38) | KIF11HSP90AA1HSP90AB1F2RTHRA | |
| SCHEMBL16959229 | 0.87 | KIF11 (0.37) | KIF11HSP90AA1HSP90AB1THRATHRB | |
| SCHEMBL16957873 | 0.79 | KIF11 (0.41) | KIF11HSP90AA1HSP90AB1NPFFR2NOTUM | |
| SCHEMBL16951924 | 0.78 | KIF11 (0.40) | KIF11HSP90AA1HSP90AB1NPFFR2PTGS2 | |
| SCHEMBL16954863 | 0.77 | AR (0.52) | AR | |
| SCHEMBL16960657 | 0.77 | HSP90AA1 (0.36) | KIF11HSP90AA1HSP90AB1THRATHRB | |
| SCHEMBL16958884 | 0.75 | MAPT (0.38) | KIF11HSP90AA1HSP90AB1NPFFR2NOTUM | |
| SCHEMBL6298331 | 0.73 | RARB (0.46) | KIF11NOTUMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6319525 | 0.70 | HSD17B3 (0.44) | THRBPTGS2PTGS1ALOX5MEN1 | |
| SCHEMBL16954461 | 0.69 | AR (0.54) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |