Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961875 | 0.86 | NQO1 (0.39) | HPGDMAPTALDH1A1CYP2C9POLB | |
| SCHEMBL16960514 | 0.85 | POLB (0.36) | HPGDMAPTALDH1A1CYP2C9POLB | |
| SCHEMBL16960446 | 0.85 | RARA (0.41) | HPGDMAPTALDH1A1CYP2C9POLB | |
| SCHEMBL16951236 | 0.83 | HPGD (0.33) | HPGDMAPTALDH1A1CYP2C9POLB | |
| SCHEMBL16955697 | 0.81 | MAPT (0.36) | HPGDMAPTALDH1A1CYP2C9POLB | |
| SCHEMBL16953903 | 0.81 | MAOB (0.36) | HPGDMAPTALDH1A1CYP2C9POLB | |
| SCHEMBL16956981 | 0.81 | MAPT (0.36) | HPGDMAPTALDH1A1CYP2C9POLB | |
| SCHEMBL16961444 | 0.81 | FFAR4 (0.40) | HPGDMAPTALDH1A1CYP2C9POLB | |
| SCHEMBL16950354 | 0.81 | ACACB (0.35) | HPGDMAPTALDH1A1CYP2C9POLB | |
| SCHEMBL16954078 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |