Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | SOD1 | P00441 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958555 | 0.86 | HMGCR (0.33) | SCN9APDK2CCR6PPARGPPARA | |
| SCHEMBL18002442 | 0.85 | SCN9A (0.45) | SCN9APDK2CCR6RXRARXRB | |
| SCHEMBL13155574 | 0.84 | SCN9A (0.54) | SCN9APDK2CCR6RXRARXRB | |
| SCHEMBL16955834 | 0.83 | RXRA (0.47) | RXRARXRBRXRGSOD1PPARG | |
| SCHEMBL16951519 | 0.80 | FFAR4 (0.40) | SCN9APDK2 | |
| SCHEMBL16953299 | 0.78 | ESR1 (0.39) | PPARGPPARAPPARD | |
| SCHEMBL16962138 | 0.78 | KMT2A (0.36) | PDK2 | |
| SCHEMBL16952661 | 0.78 | CYP1A1 (0.44) | PTGS1 | |
| SCHEMBL16953751 | 0.77 | PTGS1 (0.50) | RXRARXRBRXRGPTGS1 | |
| SCHEMBL16954802 | 0.77 | SCN9A (0.46) | SCN9APDK2CCR6RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |