Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SOD1 | P00441 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959744 | 0.86 | POLB (0.35) | SCN9APDK2POLBMAPTHPGD | |
| SCHEMBL13155574 | 0.85 | SCN9A (0.54) | SCN9APDK2CCR6SOD1RXRA | |
| SCHEMBL16962676 | 0.82 | RXRA (0.48) | MAOBCES2NPSR1SOD1POLB | |
| SCHEMBL16950724 | 0.79 | FFAR4 (0.41) | PDK2MAOBPOLBMAPTHPGD | |
| SCHEMBL16953371 | 0.78 | PLA2G2A (0.43) | PDK2PPARGPPARA | |
| SCHEMBL16951075 | 0.78 | SCN9A (0.45) | SCN9APDK2CCR6SOD1RXRA | |
| SCHEMBL16955248 | 0.77 | SCN9A (0.45) | SCN9APDK2CCR6SOD1RXRA | |
| SCHEMBL16959501 | 0.77 | MEN1 (0.39) | NPSR1POLBMAPTHPGDXBP1 | |
| SCHEMBL16958080 | 0.77 | POLB (0.37) | POLBMAPTHPGDXBP1KAT6A | |
| SCHEMBL16955748 | 0.77 | HPGD (0.43) | MAOBPOLBMAPTHPGDXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |