Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950711 | 0.88 | TUBB4A (0.49) | ALDH1A1TDP1LMNAMAPTKDM4E | |
| SCHEMBL16961070 | 0.84 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL16952376 | 0.84 | MAPT (0.50) | ALDH1A1TDP1LMNAMAPTKDM4E | |
| SCHEMBL16950722 | 0.81 | AKR1C3 (0.33) | ALDH1A1TDP1LMNAMAPTKDM4E | |
| SCHEMBL12040936 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL16950539 | 0.80 | MAPT (0.47) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL18970268 | 0.80 | ALDH1A1 (0.51) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL16959143 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNASIRT6CYP3A4 | |
| SCHEMBL16959353 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNASIRT6MAPT | |
| SCHEMBL24346247 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNASIRT6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |