Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957076 | 0.94 | CNR1 (0.35) | CNR1CNR2PTGS2CYP3A4LPL | |
| SCHEMBL16957769 | 0.92 | HPGD (0.47) | PTGS2CYP3A4GPR84HTTNPC1 | |
| SCHEMBL16956255 | 0.87 | FFAR4 (0.36) | CNR1CNR2PTGS2CYP3A4LPL | |
| SCHEMBL16958684 | 0.87 | GABRA1 (0.33) | CNR1CNR2GPR84NPC1RAB9A | |
| SCHEMBL16957595 | 0.86 | HPGD (0.50) | PTGS2CYP3A4GPR84HTTNPC1 | |
| SCHEMBL16950350 | 0.86 | CNR1 (0.33) | CNR1CNR2PTGS2CYP3A4LPL | |
| SCHEMBL16951949 | 0.86 | POLB (0.34) | CNR1CNR2PTGS2CYP3A4LPL | |
| SCHEMBL16952299 | 0.86 | CNR2 (0.35) | CNR1CNR2PTGS2CYP3A4LPL | |
| SCHEMBL16955782 | 0.86 | CNR1 (0.33) | CNR1CNR2PTGS2CYP3A4LPL | |
| SCHEMBL16953452 | 0.82 | HMGCR (0.36) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |