Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960926 | 0.89 | NPC1 (0.43) | GAASMN1; SMN2CYP3A4PTGS2THRB | |
| SCHEMBL16955630 | 0.86 | CNR1 (0.39) | CNR1CNR2CYP3A4PTGS2LPL | |
| SCHEMBL16960038 | 0.84 | AKR1C4 (0.32) | POLBKDM4EMEN1GAAMAPT | |
| SCHEMBL16953514 | 0.81 | THRB (0.33) | POLBCTDSP1THRB | |
| SCHEMBL18003118 | 0.81 | ALDH1A1 (0.39) | POLBCTDSP1SMN1; SMN2SLC6A19AKR1C4 | |
| SCHEMBL16957076 | 0.80 | CNR1 (0.35) | CNR1CNR2CYP3A4PTGS2LPL | |
| SCHEMBL18854254 | 0.79 | POLB (0.38) | POLBCTDSP1CNR1CNR2CYP3A4 | |
| SCHEMBL11819334 | 0.79 | IDO1 (0.41) | POLBCTDSP1CNR1CNR2CYP3A4 | |
| SCHEMBL16956255 | 0.78 | FFAR4 (0.36) | CNR1CNR2KDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL16957769 | 0.78 | HPGD (0.47) | CYP3A4PTGS2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |