Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956973 | 0.82 | CHRNB2 (0.41) | NPC1RAB9AMEN1KMT2ACHRNB2 | |
| SCHEMBL16955208 | 0.79 | TRPV1 (0.37) | MCL1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30888638 | 0.77 | PTGDR2 (0.45) | PTGDR2MEN1KMT2AHTR2CCHRNA7 | |
| SCHEMBL16954015 | 0.77 | MEN1 (0.41) | PTGDR2MEN1KMT2AHTR2CCHRNA7 | |
| SCHEMBL16953407 | 0.77 | CHRNB2 (0.38) | PTGDR2HTR2CCHRNB2CHRNA4NOS3 | |
| SCHEMBL15718389 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2AHTR2CNOS3NOS1 | |
| SCHEMBL23268487 | 0.74 | MEN1 (0.58) | PTGDR2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31172738 | 0.74 | MEN1 (0.58) | PTGDR2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3692141 | 0.74 | MEN1 (0.58) | PTGDR2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6872023 | 0.74 | PROKR1 (0.44) | PTGDR2MEN1KMT2AHTR2CCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |