Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.43 |
| ▸ | THRA | P10827 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950978 | 0.90 | THRB (0.40) | THRBTHRAMEN1KMT2ACNR2 | |
| SCHEMBL16951604 | 0.89 | THRB (0.49) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16957427 | 0.85 | THRB (0.46) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16954686 | 0.84 | THRB (0.45) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16953900 | 0.83 | — | — | |
| SCHEMBL16957869 | 0.83 | THRB (0.44) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16951598 | 0.83 | THRB (0.44) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16958361 | 0.82 | HPGD (0.44) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16959285 | 0.81 | THRB (0.43) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16954186 | 0.80 | ACHE (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |