Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | MAOA | P21397 | 5/20 | 0.46 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311628 | 0.82 | MAOB (0.41) | MAOBMAOASLC1A5NOS3NOS1 | |
| SCHEMBL30475151 | 0.78 | MAOB (0.61) | MAOBMAOASLC1A5NOS3NOS1 | |
| SCHEMBL1395661 | 0.78 | MAOB (0.61) | MAOBMAOASLC1A5NOS3NOS1 | |
| SCHEMBL1343170 | 0.76 | MAOB (0.48) | MAOBMAOASLC1A5NOS3NOS1 | |
| SCHEMBL16961222 | 0.76 | MAOB (0.48) | MAOBMAOASLC1A5NOS3NOS1 | |
| SCHEMBL5642351 | 0.74 | IMPDH2 (0.41) | TRPV4ALDH1A1 | |
| SCHEMBL1906136 | 0.73 | MAOB (0.46) | MAOBMAOASLC1A5NOS3NOS1 | |
| SCHEMBL16534885 | 0.73 | MAOB (0.50) | MAOBMAOASLC1A5NOS3NOS1 | |
| SCHEMBL267151 | 0.73 | TRPV4 (0.57) | MAOBMAOASLC1A5CYP11B1CYP11B2 | |
| SCHEMBL7485092 | 0.73 | MAOB (0.46) | MAOBMAOASLC1A5NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023080732-A1 | COMPOUND HAVING BTK PROTEIN DEGRADATION ACTIVITY, AND MEDICAL USES THEREOF | 주식회사 유빅스테라퓨틱스 | 2023-05-11 | — | — | WO | disclosed |
| CN-106459002-A | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |