Glycerin

Glycerin

SCHEMBL1695600

O=C(O)O.O=C1OCC(CO)O1.OCC(O)CO

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1605312 0.85 KDM4E (0.33) LMNA
SCHEMBL8917948 0.84
SCHEMBL47782 0.84
Oxirane SCHEMBL23581830 0.78 LMNA (0.31) LMNA
Acrylic Acid SCHEMBL23581832 0.78 LMNA (0.34) LMNA
Butane SCHEMBL28612846 0.77 PTPN1 (0.36)
Methacrylic Acid SCHEMBL5597048 0.77 ALDH1A1 (0.34) ALDH1A1
Methacrylic Acid SCHEMBL22204657 0.77 ALDH1A1 (0.34) ALDH1A1
Glycerin SCHEMBL4073831 0.76 ALDH1A1 (0.39) ALDH1A1LMNA
SCHEMBL16769340 0.74 ALDH1A1 (0.41) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107522-A1 DENTAL COMPOSITION AND USE THEREOF 3M Innovative Properties Company (US) 2016-12-28 EP disclosed
WO-2015126666-A1 DENTAL COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-08-27 WO disclosed
WO-2011157551-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXYLIC ACID AND DERIVATIVES THEREOF, THEIR PREPARATION AND USE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2011-12-22 WO disclosed
EP-2358838-A1 DENSITY-MATCHED SUSPENSIONS AND ASSOCIATED METHODS Halliburton Energy Services, Inc. (US) 2011-08-24 EP disclosed