Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2106728 | 0.78 | CES2 (0.42) | HTTPARP1MAOAMAOBMAPT | |
| SCHEMBL3096979 | 0.76 | PARP1 (0.56) | HTTKDM4EPARP1KMT2AMEN1 | |
| SCHEMBL4375606 | 0.76 | PARP1 (0.56) | HTTKDM4EPARP1KMT2AMEN1 | |
| SCHEMBL17244256 | 0.76 | PARP1 (0.57) | HTTPARP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16952021 | 0.76 | CES2 (0.50) | HTTKDM4EPARP1KMT2AMEN1 | |
| SCHEMBL20659172 | 0.75 | HTT (0.50) | HTTKDM4EPARP1KMT2AMEN1 | |
| SCHEMBL24710340 | 0.75 | HTT (0.50) | HTTKDM4EPARP1KMT2AMEN1 | |
| SCHEMBL13335454 | 0.75 | HTT (0.50) | HTTKDM4EPARP1KMT2AMEN1 | |
| SCHEMBL28365847 | 0.75 | HTT (0.50) | HTTKDM4EPARP1KMT2AMEN1 | |
| SCHEMBL16951392 | 0.74 | PARP1 (0.54) | HTTKDM4EPARP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |