Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375606 | 0.85 | PARP1 (0.56) | PARP1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL16951392 | 0.83 | PARP1 (0.54) | PARP1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL13221047 | 0.81 | CTSL (0.54) | PARP1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL1361076 | 0.81 | PARP1 (0.52) | PARP1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL54859 | 0.81 | PARP1 (0.63) | PARP1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL23931574 | 0.81 | PARP1 (0.63) | PARP1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL13478834 | 0.81 | PARP1 (0.52) | PARP1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL17187940 | 0.81 | PARP1 (0.63) | PARP1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL21981592 | 0.81 | PARP1 (0.52) | PARP1HTTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL16364221 | 0.81 | PARP1 (0.52) | PARP1HTTKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836280-A | Preparation method of 4-bromo-isothiazolinone derivative and 4-bromo-isothiazolinone derivative | 奥加诺株式会社 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023032654-A1 | PRODUCTION METHOD FOR 4-BROMOISOTHIAZOLINONE DERIVATIVE AND 4-BROMOISOTHIAZOLINONE DERIVATIVE | オルガノ株式会社 | 2023-03-09 | — | — | WO | disclosed |
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-10-22 | — | — | US | disclosed |
| EP-3157920-B1 | INDOLIZINE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2019-08-07 | — | — | EP | disclosed |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| CN-105358534-A | Novel synthetic process to 8-chloro-1-methyl-benzo[d]azepine, novel intermediates and the production thereof | LEK PHARMACEUTICALS | 2016-02-24 | — | — | CN | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| WO-2012163959-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-12-06 | — | — | WO | disclosed |
| CN-101817784-B | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES CO., LTD. (JP) | 2012-02-01 | — | — | CN | disclosed |
| US-20100234220-A1 | Oxooxetanes as Fungicidal Agents | BAYER CROPSCIENCE AG (DE) | 2010-09-16 | — | — | US | disclosed |
| US-6063734-A | AGRICULTURAL CHEMICALS, AGENTS FOR PREVENTING ATTACHMENT OF AQUATIC ORGANISMS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5965613-A | FUNGICIDES FOR USE IN AGRICULTURE AND HORTICULTURE; THE COMPOUNDS ALSO HAVE INSECTICIDAL AND ACARICIDAL ACTIVITY | NOVARTIS FINANCE CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| CN-1216530-A | Ethylene derivatives and pesticides containing the same | NISSAN CHEMICAL IND LTD (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0913392-A1 | ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0635485-B1 | TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEM RES (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5554581-A | Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-09-10 | — | — | US | disclosed |
| US-5506190-A | Tetrahydrophthalamide derivative, intermediate for producing the same, production of both, and herbicide containing the same as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-04-09 | — | — | US | disclosed |
| US-5466697-A | 8-phenyl-1,6-naphthyridin-5-ones | SYNTEX (U.S.A.) INC. (US) | 1995-11-14 | — | — | US | disclosed |
| EP-0635485-A1 | TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | CBR1, HAO2, CBR3 | PARP1 1166/4885HTT 2609/4885KDM4E 4342/4885 |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | CBR1, HAO2, CBR3 | PARP1 1166/4885HTT 2609/4885KDM4E 4342/4885 |
| US-20100234220-A1 | Oxooxetanes as Fungicidal Agents | CYP51A1, PNPO, AOX1 | PARP1 4378/4885HTT 2706/4885KDM4E 1337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.