SCHEMBL1695650

SCHEMBL1695650

O=C(O)/C(=C/c1ccc(Cl)cc1)c1ccc(O)cc1

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.73
HTT P42858 1/20 0.73
AKR1C3 P42330 7/20 0.68
AKR1C1 Q04828 6/20 0.68
AKR1C2 P52895 5/20 0.68
PTGS2 P35354 3/20 0.63
CXCL12 P48061 1/20 0.54
MAOB P27338 1/20 0.54
MAPK1 P28482 1/20 0.53
MEN1 O00255 1/20 0.50
POLB P06746 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1695651 1.00 ALDH1A1 (0.73) ALDH1A1HTTAKR1C3AKR1C1AKR1C2
SCHEMBL10950320 0.93 ALDH1A1 (0.83) ALDH1A1HTTAKR1C3AKR1C1AKR1C2
SCHEMBL10950323 0.93 ALDH1A1 (0.83) ALDH1A1HTTAKR1C3AKR1C1AKR1C2
SCHEMBL28931332 0.91 PTGS2 (0.73) ALDH1A1HTTAKR1C3AKR1C1AKR1C2
SCHEMBL11685143 0.86 HTT (0.55) ALDH1A1HTTAKR1C3AKR1C1AKR1C2
SCHEMBL11685151 0.86 HTT (0.55) ALDH1A1HTTAKR1C3AKR1C1AKR1C2
SCHEMBL20184151 0.86 AKR1C1 (0.75) ALDH1A1HTTAKR1C3AKR1C1AKR1C2
SCHEMBL7814857 0.86 AKR1C1 (0.75) ALDH1A1HTTAKR1C3AKR1C1AKR1C2
SCHEMBL11328602 0.86 AKR1C1 (0.75) ALDH1A1HTTAKR1C3AKR1C1AKR1C2
SCHEMBL7814861 0.86 AKR1C1 (0.75) ALDH1A1HTTAKR1C3AKR1C1AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9720136-B2 Photo-alignment copolymer, optical anistropic film and its preparation method LG CHEM, LTD. (KR) 2017-08-01 US disclosed
US-20150219794-A1 PHOTO-ALIGNMENT COPOLYMER, OPTICAL ANISTROPIC FILM AND ITS PREPARATION METHOD (As Amended) LG CHEM, LTD. (KR) 2015-08-06 US disclosed
WO-2011138657-A1 ARYL SUBSTITUTED OLEFINIC COMPOUNDS AS PDE10A INHIBITORS GLENMARK PHARMACEUTICALS S.A. (CH) 2011-11-10 WO disclosed