Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.40 |
| ▸ | THRA | P10827 | 5/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959148 | 0.91 | THRB (0.37) | THRBTRPV1TACR1CES2 | |
| SCHEMBL16962459 | 0.87 | THRB (0.41) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16958887 | 0.85 | NOTUM (0.36) | PTGS2CES2 | |
| SCHEMBL16951604 | 0.85 | THRB (0.49) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16954757 | 0.83 | NPC1 (0.41) | TRPV1NPC1HPGDMAPK1HTT | |
| SCHEMBL16957427 | 0.82 | THRB (0.46) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16959285 | 0.81 | THRB (0.43) | THRBTHRATRPV1NPC1HPGD | |
| SCHEMBL16954686 | 0.80 | THRB (0.45) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16960451 | 0.80 | THRB (0.38) | THRBTHRANPC1HPGDMAPK1 | |
| SCHEMBL16956391 | 0.79 | TRPV1 (0.38) | TRPV1NPC1HPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |