Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956667 | 0.91 | THRB (0.40) | THRBCES2TACR1TRPV1 | |
| SCHEMBL16958887 | 0.88 | NOTUM (0.36) | CES2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL16952827 | 0.86 | THRB (0.38) | THRBRXRARXRBRXRG | |
| SCHEMBL16960465 | 0.84 | THRB (0.46) | THRBALDH1A1TRPV1 | |
| SCHEMBL16952850 | 0.82 | CES2 (0.38) | CES2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL16962628 | 0.82 | CES2 (0.48) | CES2RXRARXRBRXRGNOTUM | |
| SCHEMBL16952286 | 0.80 | THRB (0.40) | THRBALDH1A1 | |
| SCHEMBL16953002 | 0.79 | THRB (0.42) | THRBRXRARXRBTRPV1 | |
| SCHEMBL16955954 | 0.78 | CES2 (0.35) | CES2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL16962459 | 0.78 | THRB (0.41) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |