Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961012 | 0.84 | FGFR1 (0.38) | AHRFAAH | |
| SCHEMBL16959787 | 0.84 | AHR (0.50) | AHRLTA4HNR5A1TLR4TLR2 | |
| SCHEMBL12968136 | 0.83 | ALDH1A1 (0.45) | AHRFAAHTLR4TLR2PLA2G2A | |
| SCHEMBL16958797 | 0.83 | AHR (0.43) | AHRLTA4HNR5A1FAAHTLR4 | |
| SCHEMBL16959384 | 0.83 | ALDH1A1 (0.38) | — | |
| SCHEMBL16957714 | 0.83 | AHR (0.49) | AHRLTA4HNR5A1TLR4TLR2 | |
| SCHEMBL9242292 | 0.82 | LTA4H (0.45) | AHRLTA4HNR5A1FAAHPLA2G2A | |
| SCHEMBL16961616 | 0.81 | AHR (0.44) | AHRLTA4HNR5A1TLR4TLR2 | |
| SCHEMBL16952043 | 0.81 | — | — | |
| SCHEMBL16960150 | 0.80 | AHR (0.43) | AHRLTA4HNR5A1TLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |