Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280284 | 0.85 | SMO (0.54) | SMONPSR1SMN1; SMN2LMNARAB9A | |
| SCHEMBL9363470 | 0.85 | SMO (0.54) | SMONPSR1SMN1; SMN2LMNARAB9A | |
| SCHEMBL11381573 | 0.83 | NPSR1 (0.55) | SMONPSR1SMN1; SMN2LMNARAB9A | |
| SCHEMBL13719047 | 0.81 | HPGD (0.53) | SMONPSR1SMN1; SMN2LMNARAB9A | |
| SCHEMBL13602488 | 0.77 | SMN1; SMN2 (0.57) | SMONPSR1SMN1; SMN2LMNARAB9A | |
| SCHEMBL27861242 | 0.72 | SMN1; SMN2 (0.65) | NPSR1SMN1; SMN2LMNARAB9AALDH1A1 | |
| SCHEMBL14113376 | 0.71 | LMNA (0.56) | NPSR1SMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL12770960 | 0.70 | MEN1 (0.68) | SMONPSR1SMN1; SMN2LMNARAB9A | |
| SCHEMBL6681735 | 0.70 | HPGD (0.69) | SMN1; SMN2LMNARAB9AALDH1A1NPC1 | |
| SCHEMBL1267498 | 0.70 | SMN1; SMN2 (0.66) | NPSR1SMN1; SMN2LMNARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426130-A1 | PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 2012-03-07 | — | — | EP | disclosed |