Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPD | P32754 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961929 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2APKMHPDALDH1A1 | |
| SCHEMBL16956549 | 0.81 | ATM (0.50) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL16960041 | 0.80 | KMT2A (0.38) | MEN1KMT2AALDH1A1MAPTTXNRD1 | |
| SCHEMBL16956853 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2APKMHPDALDH1A1 | |
| SCHEMBL16959573 | 0.78 | MAPK1 (0.50) | MEN1KMT2APKMALDH1A1MAPT | |
| SCHEMBL16962072 | 0.78 | S100A4 (0.37) | MEN1KMT2APKMMAPK1CYP3A4 | |
| SCHEMBL16959338 | 0.78 | TSHR (0.51) | MEN1KMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL16960002 | 0.75 | ALDH1A1 (0.50) | MEN1KMT2APKMHPDALDH1A1 | |
| SCHEMBL16957264 | 0.75 | PDE2A (0.42) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16952607 | 0.74 | GRM8 (0.48) | MEN1KMT2AALDH1A1MAPK1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |