Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953498 | 0.84 | HPGD (0.34) | SMN1; SMN2LMNAALDH1A1HTTHPGD | |
| SCHEMBL16960018 | 0.84 | KDM4E (0.39) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL16961643 | 0.83 | HPGD (0.48) | SMN1; SMN2LMNAALDH1A1HTTHPGD | |
| SCHEMBL16955569 | 0.83 | IDO1 (0.38) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL16960402 | 0.82 | ALDH1A1 (0.40) | SMN1; SMN2LMNAALDH1A1POLBMAPT | |
| SCHEMBL16962915 | 0.81 | CSNK2A1 (0.40) | SMN1; SMN2LMNAALDH1A1HPGDTSHR | |
| SCHEMBL16954024 | 0.81 | KCNH2 (0.36) | MAPTHPGDMEN1KMT2ACSNK2A1 | |
| SCHEMBL16950480 | 0.81 | IRAK4 (0.37) | ARPTGDR2 | |
| SCHEMBL16955958 | 0.80 | ADRA1A (0.45) | HTTMEN1KMT2ANPSR1 | |
| SCHEMBL5884350 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2LMNAALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |