Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959503 | 0.87 | KAT6A (0.46) | KAT6AGABRA1GABRB2CLCN2RIPK1 | |
| SCHEMBL16951986 | 0.87 | PDCD1 (0.35) | KAT6AGABRA1GABRB2CES2BCHE | |
| SCHEMBL16951874 | 0.86 | KAT6A (0.34) | KAT6AGABRA1GABRB2RIPK1DAO | |
| SCHEMBL16951653 | 0.82 | KAT6A (0.48) | KAT6AGABRA1GABRB2CLCN2RIPK1 | |
| SCHEMBL4876639 | 0.81 | KAT6A (0.50) | KAT6AGABRA1GABRB2CLCN2RIPK1 | |
| SCHEMBL16950705 | 0.81 | GABRA1 (0.45) | GABRA1GABRB2CLCN2MRGPRX4HTT | |
| SCHEMBL18866792 | 0.79 | KAT6A (0.46) | KAT6AGABRA1GABRB2CLCN2RIPK1 | |
| SCHEMBL16962140 | 0.79 | GABRA1 (0.43) | KAT6AGABRA1GABRB2CLCN2MRGPRX4 | |
| SCHEMBL16953106 | 0.79 | CES2 (0.31) | CES2BCHECES1 | |
| SCHEMBL16954240 | 0.79 | CES2 (0.52) | KAT6ARIPK1CES2BCHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |