Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951517 | 0.85 | BACE1 (0.36) | MAPTBACE1ALDH1A1LMNAPTGER4 | |
| SCHEMBL16960748 | 0.83 | CYP4F2 (0.38) | ALDH1A1LMNAPTGER4POLBMEN1 | |
| SCHEMBL14190481 | 0.82 | FFAR4 (0.43) | CETPMAPTALDH1A1POLBGRIN1 | |
| SCHEMBL16955237 | 0.81 | FFAR4 (0.33) | ALDH1A1LMNAPTGER4POLBTACR1 | |
| SCHEMBL16950695 | 0.81 | MAPT (0.36) | MAPTALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL16960385 | 0.81 | ALDH1A1 (0.41) | MAPTALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL22181429 | 0.81 | CYP4F2 (0.39) | MAPTBACE1ALDH1A1LMNARXRA | |
| SCHEMBL16958445 | 0.79 | RXRA (0.32) | MAPTBACE1ALDH1A1RXRAGRIN1 | |
| SCHEMBL16960861 | 0.79 | CYP4F2 (0.38) | BACE1RXRAGRIN1GRIN2BMEP1B | |
| SCHEMBL15864520 | 0.78 | POLB (0.42) | ALDH1A1LMNAPTGER4POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |