Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960112 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HIF1AGPR35TSHRLMNA | |
| SCHEMBL1030342 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HIF1AGPR35TSHRLMNA | |
| SCHEMBL29744802 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HIF1AGPR35TSHRLMNA | |
| SCHEMBL16953608 | 0.80 | PTPRC (0.41) | ALDH1A1HIF1AGPR35TSHRLMNA | |
| SCHEMBL16951755 | 0.80 | HSD17B10 (0.55) | ALDH1A1TSHRLMNATDP1HSD17B10 | |
| SCHEMBL16958012 | 0.80 | LMNA (0.42) | ALDH1A1GPR35TSHRLMNATDP1 | |
| SCHEMBL16952989 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TSHRLMNATDP1HSD17B10 | |
| SCHEMBL16950964 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HIF1AGPR35TSHRLMNA | |
| SCHEMBL16960626 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNATDP1HSD17B10 | |
| SCHEMBL16961858 | 0.78 | ALDH1A1 (0.49) | ALDH1A1HIF1AGPR35TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |