SCHEMBL16958713

SCHEMBL16958713

[CH2]c1cc(Br)cc(CC)c1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.32
IDO1 P14902 1/20 0.32
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16955115 0.82 POLB (0.33) IDO1
SCHEMBL608334 0.82 PTGS2 (0.39) PTGS2
SCHEMBL1437868 0.82 PTGS2 (0.39) PTGS2IDO1MAPTHTTSMN1; SMN2
SCHEMBL811745 0.82 IDO1 (0.44) PTGS2IDO1MAPTHTTSMN1; SMN2
SCHEMBL16955109 0.79 NPC1 (0.42) PTGS2HTTSMN1; SMN2
SCHEMBL28254121 0.78 IDO1 (0.33) IDO1
Nitrogen SCHEMBL27562848 0.77 PTGS2 (0.36) PTGS2IDO1MAPTHTTSMN1; SMN2
SCHEMBL16951374 0.76 GABRA1 (0.33) MAPT
Methoxymethane SCHEMBL27562970 0.75 PTGS2 (0.44) PTGS2IDO1MAPTHTTSMN1; SMN2
SCHEMBL12514812 0.73 TACR1 (0.41) PTGS2IDO1MAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed