SCHEMBL16958727

SCHEMBL16958727

C=Cc1cc(OC(F)(F)F)ccc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 5/20 0.45
RET P07949 1/20 0.39
FFAR4 Q5NUL3 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
GAA P10253 2/20 0.37
SCN5A Q14524 2/20 0.37
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
CYP2C9 P11712 1/20 0.37
PKM P14618 1/20 0.37
ALOX15 P16050 1/20 0.37
NFKB1 P19838 1/20 0.37
SLC6A2 P23975 1/20 0.37
SCN4A P35499 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25996829 0.86 GPR3 (0.45) GPR3RETFFAR4NPC1RAB9A
SCHEMBL17822065 0.82 GPR3 (0.41) GPR3RETFFAR4NPC1RAB9A
SCHEMBL16951948 0.82 GPR3 (0.41) GPR3RETFFAR4NPC1RAB9A
SCHEMBL16955162 0.80 GPR3 (0.42) GPR3FFAR4NPC1RAB9AGAA
SCHEMBL16953635 0.80 GPR3 (0.42) GPR3NPC1RAB9AGAASCN5A
SCHEMBL17821943 0.79 GPR3 (0.40) GPR3RETFFAR4NPC1RAB9A
SCHEMBL16959108 0.79 CYP1A1 (0.44) GPR3CYP1A2NFKB1
SCHEMBL17821944 0.79 GPR3 (0.40) GPR3RETFFAR4NPC1RAB9A
SCHEMBL11351024 0.79 KMT2A (0.36) NPC1RAB9AGAALMNATP53
SCHEMBL16950613 0.79 GPR3 (0.41) GPR3NPC1RAB9AGAASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed