Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11986284 | 0.85 | ERN1 (0.44) | KMT2ALMNASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL12885255 | 0.80 | ALDH1A1 (0.41) | KMT2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL16959829 | 0.80 | NQO1 (0.46) | KMT2ASMN1; SMN2MAPTMEN1HPGD | |
| SCHEMBL27238978 | 0.79 | NR4A1 (0.37) | KMT2ALMNAL3MBTL1GFERSMN1; SMN2 | |
| SCHEMBL16958727 | 0.79 | GPR3 (0.45) | LMNASMN1; SMN2MAPTTP53NPC1 | |
| SCHEMBL27411549 | 0.75 | PTGS1 (0.39) | HPGDALDH1A1TSHR | |
| SCHEMBL87447 | 0.75 | ALOX5 (0.47) | KMT2ALMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL29392003 | 0.75 | ALOX5 (0.47) | KMT2ALMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL23640007 | 0.74 | HTR1B (0.46) | LMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL19935690 | 0.74 | CYP3A4 (0.35) | LMNAALDH1A1NR4A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768459-A | Improving immune response and reducing immune paralysis by immunomodulating therapy | 西托索尔本茨公司 | 2023-03-07 | — | — | CN | disclosed |
| US-4304639-A | DISTILLATION | PROPYLOX (SOCIETE ANONYME) (BE) | 1981-12-08 | — | — | US | disclosed |