SCHEMBL16958766

SCHEMBL16958766

[CH2]C(C=C)c1cccc(OCCC)c1C#N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
MAPT P10636 3/20 0.34
HPGD P15428 2/20 0.34
MCHR1 Q99705 1/20 0.34
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
IKBKB O14920 1/20 0.33
POLB P06746 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
NPSR1 Q6W5P4 2/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16956768 0.90 MEN1 (0.38) NPC1RAB9AALDH1A1KDM4EMAPT
SCHEMBL16958260 0.86 CYP2A6 (0.38) CYP2A6NPC1RAB9AALDH1A1KDM4E
SCHEMBL16954628 0.82 CYP2A6 (0.35) CYP2A6NPC1RAB9AALDH1A1KDM4E
SCHEMBL16958573 0.81 NPC1 (0.41) NPC1RAB9AALDH1A1KDM4EMAPT
SCHEMBL16955017 0.80 MCHR1 (0.37) CYP2A6ALDH1A1MAPTMCHR1KMT2A
SCHEMBL16951221 0.80 HTR1B (0.37) CYP2A6ALDH1A1KDM4EMAPTHPGD
SCHEMBL16951235 0.78 MCHR1 (0.36) CYP2A6ALDH1A1KDM4EMAPTHPGD
SCHEMBL16954204 0.78 L3MBTL1 (0.36) CYP2A6NPC1RAB9AALDH1A1MAPT
SCHEMBL16955705 0.78 ALDH1A1 (0.38) CYP2A6NPC1RAB9AALDH1A1KDM4E
SCHEMBL16959102 0.78 VEGFA (0.40) ALDH1A1MAPTMCHR1PRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed