Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.43 |
| ▸ | MELK | Q14680 | 1/20 | 0.43 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PNMT | P11086 | 2/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40188 | 0.81 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL8927858 | 0.81 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1TSHRGSRLMNA | |
| SCHEMBL30587141 | 0.81 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL16957677 | 0.78 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP1A2CYP2A6 | |
| SCHEMBL16934060 | 0.78 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL16934056 | 0.78 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL5491734 | 0.76 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL3302004 | 0.75 | PPP1R15A (0.48) | ALDH1A1L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL10438866 | 0.74 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1PPP1R15AMELKPPP1R15B | |
| SCHEMBL29010084 | 0.73 | PPP1R15A (0.47) | ALDH1A1L3MBTL1PPP1R15AMELKPPP1R15B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |