SCHEMBL40188

SCHEMBL40188

C=Cc1cccc(Cl)c1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
PPP1R15A O75807 1/20 0.46
MELK Q14680 1/20 0.46
PPP1R15B Q5SWA1 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TSHR P16473 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
PNMT P11086 2/20 0.39
GSR P00390 1/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 3/20 0.37
PTGS2 P35354 1/20 0.37
DYRK1A Q13627 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30587141 1.00 ALDH1A1 (0.65) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL5491734 0.93 ALDH1A1 (0.78) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL10438866 0.91 ALDH1A1 (0.56) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL16960550 0.87 ALDH1A1 (0.59) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL9985258 0.86 ALDH1A1 (0.55) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL11856700 0.84 ALDH1A1 (0.53) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL15753874 0.83 ALDH1A1 (0.47) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL12080115 0.82 ALDH1A1 (0.50) ALDH1A1CYP1A2KMT2AMEN1LMNA
SCHEMBL16959080 0.81 ALDH1A1 (0.48) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL7252561 0.81 ALDH1A1 (0.60) ALDH1A1PPP1R15AMELKPPP1R15BNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15057 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352782-B1 None US claimed
CN-122080317-A Method for preparing low-glossiness low-odor ABS resin and application thereof 2026-05-26 CN claimed
US-20260040695-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NEWSOUTH INNOVATIONS PTY LTD (AU) 2026-02-05 US claimed
EP-4045585-B1 POLYBUTYLENE TEREPHTHALATE COMPOSITION AND ARTICLE THEREOF BASF SE (DE) 2025-12-10 EP claimed
WO-2025223777-A1 POLYOLEFIN COPOLYMER-BASED HOTMELTS FOR LOW PRESSURE MOLDING MANUFACTURING OF ARTICLES WITH GOOD ALCOHOL RESISTANCE HENKEL AG & CO. KGAA (DE) 2025-10-30 WO claimed
EP-4640398-A1 POLYOLEFIN COPOLYMER-BASED HOTMELTS FOR LOW PRESSURE MOLDING MANUFACTURING OF ARTICLES WITH GOOD ALCOHOL RESISTANCE Henkel AG & Co. KGaA (DE) 2025-10-29 EP claimed
US-20250304513-A1 Oligomeric Product Made Out of Pyrolysis Oil Via a Polymerization TOTALENERGIES ONETECH (FR) 2025-10-02 US claimed
US-20250263535-A1 RUBBER PRODUCT MADE OUT OF PYROLYSIS OIL VIA A POLYMERIZATION TOTALENERGIES ONETECH (FR) 2025-08-21 US claimed
US-20250263585-A1 ADHESIVE PRODUCT MADE OUT OF PYROLYSIS OIL VIA A POLYMERIZATION TOTALENERGIES ONETECH (FR) 2025-08-21 US claimed
EP-4562077-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NewSouth Innovations Pty Limited (AU) 2025-06-04 EP claimed
US-4129707-A Bead size distribution in the suspension polymerization of vinyl aromatic monomers employing aminoalkanesulfonic acids ARCO POLYMERS, INC. (US) 1978-12-12 US claimed
US-4125573-A Polymer polyblend composition MONSANTO COMPANY (US) 1978-11-14 US claimed
US-4097549-A POLYMER WITH AT LEAST ONE MONOALKENYL AROMATIC MONOMER, DIENE RUBBER, RUBBER PARTICLES MONSANTO COMPANY (US) 1978-06-27 US claimed
US-4092469-A OF CONJUGATED DIENES, BIS(1,3-DIENYL)DIALKYL TIN, LEAD, OR GERMANIUM PHILLIPS PETROLEUM COMPANY (US) 1978-05-30 US claimed
US-4064337-A Mixing of organosulfur molecular weight modifier with emulsifier for emulsion polymerization systems PHILLIPS PETROLEUM COMPANY (US) 1977-12-20 US claimed
US-4051214-A METHOD OF CONTROLLING MONOMER LOSS DURING THE PRODUCTION OF A FIBER-THERMOPLASTIC MATRIX BY IN SITU BULK POLYMERIZATION WEYERHAEUSER COMPANY (US) 1977-09-27 US claimed
US-4041227-A USING BIS(1,3-DIENYL)DIALKYLTIN, -LEAD, OR -GERMANIUM IN THE POLYMERIZATION OF CONJUGATED DIENE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1977-08-09 US claimed
US-4027063-A CIRCUIT BOARDS, METH-ACRYLOYLOXY-TERMINATED BUTADIENE RESIN, HALOGEN CONTAINING MONOMER AND UNSATURATED ANHYDRIDE SONY CORPORATION (JA) 1977-05-31 US claimed
US-3969433-A ADDITION POLYMER KOSE AKIRA 1976-07-13 US claimed
US-3965230-A Process of manufacturing lacquered articles of cold rolled abs resin MONSANTO COMPANY (US) 1976-06-22 US claimed