Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961470 | 0.84 | P2RX7 (0.35) | TAS1R3TAS1R1TAS1R2LMNAHPGD | |
| SCHEMBL16954018 | 0.82 | TSHR (0.43) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16956072 | 0.79 | TSHR (0.50) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16954069 | 0.79 | TSHR (0.50) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16956594 | 0.79 | TSHR (0.50) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16958412 | 0.77 | TSHR (0.48) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16951918 | 0.77 | TSHR (0.48) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16957521 | 0.76 | F2R (0.49) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16956641 | 0.73 | TSHR (0.64) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL10706917 | 0.73 | TSHR (0.58) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |