Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957521 | 0.84 | F2R (0.49) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16954069 | 0.83 | TSHR (0.50) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16956072 | 0.83 | TSHR (0.50) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL7459619 | 0.83 | CES2 (0.48) | TSHRERCC5FEN1 | |
| SCHEMBL16958412 | 0.82 | TSHR (0.48) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16957551 | 0.82 | TAS1R3 (0.38) | TSHRTAS1R3TAS1R1TAS1R2F2R | |
| SCHEMBL16951918 | 0.82 | TSHR (0.48) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16951536 | 0.81 | F2R (0.47) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16952644 | 0.79 | TSHR (0.55) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 | |
| SCHEMBL16959901 | 0.79 | TSHR (0.46) | TSHRTAS1R3TAS1R1TAS1R2ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |