Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29256486 | 1.00 | SLC18A3 (0.44) | SLC18A3SIGMAR1GRIN2BHDAC4HDAC2 | |
| SCHEMBL30988828 | 1.00 | SLC18A3 (0.44) | SLC18A3SIGMAR1GRIN2BHDAC4HDAC2 | |
| SCHEMBL30988811 | 1.00 | SLC18A3 (0.44) | SLC18A3SIGMAR1GRIN2BHDAC4HDAC2 | |
| SCHEMBL16959998 | 0.82 | HDAC4 (0.38) | SLC18A3SIGMAR1HDAC4HDAC2HDAC8 | |
| SCHEMBL13958750 | 0.81 | SLC18A3 (0.41) | SLC18A3SIGMAR1GRIN2B | |
| SCHEMBL18793787 | 0.81 | KMO (0.39) | SLC18A3HDAC4HDAC2HDAC8KMO | |
| SCHEMBL29337379 | 0.81 | BCDIN3D (0.39) | SLC18A3SIGMAR1HDAC4HDAC2HDAC8 | |
| SCHEMBL14038059 | 0.78 | TSHR (0.47) | CYP3A4TSHR | |
| SCHEMBL31085235 | 0.78 | LMNA (0.44) | SLC18A3SIGMAR1HDAC4HDAC2HDAC8 | |
| SCHEMBL16953424 | 0.76 | HDAC4 (0.42) | SIGMAR1HDAC4HDAC2HDAC8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118340754-A | Compound for treating heart failure and related diseases and application thereof | 源道医药(苏州)有限公司 | 2024-07-16 | — | — | CN | disclosed |