Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696097 | 1.00 | CHRNA7 (0.51) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL12071893 | 1.00 | CHRNA7 (0.51) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL1696093 | 1.00 | CHRNA7 (0.51) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL1696095 | 1.00 | CHRNA7 (0.51) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL1696173 | 1.00 | CHRNA7 (0.51) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL16460944 | 0.92 | CYP2D6 (0.45) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL16460946 | 0.92 | CYP2D6 (0.45) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL1696312 | 0.91 | NTMT1 (0.45) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL16476711 | 0.91 | NTMT1 (0.45) | CHRNA7BCHEACHECHRM3CHRM2 | |
| SCHEMBL1696309 | 0.91 | NTMT1 (0.45) | CHRNA7BCHEACHECHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585457-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | Chiesi Farmaceutici S.p.A. (IT) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011160918-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-12-29 | — | — | WO | disclosed |