Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853771 | 0.77 | TDP1 (0.45) | NPC1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL5404806 | 0.77 | NFE2L2 (0.36) | NPC1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL16958857 | 0.77 | ALDH1A1 (0.48) | NPC1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL5774846 | 0.77 | MAPT (0.43) | NPC1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL5774843 | 0.77 | MAPT (0.43) | NPC1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL16962237 | 0.76 | NFE2L2 (0.54) | NFE2L2CES2CES1CA3CA6 | |
| SCHEMBL16961854 | 0.76 | TSHR (0.48) | MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL16960982 | 0.76 | NFE2L2 (0.39) | NPC1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL16957954 | 0.74 | F2RL1 (0.40) | NPC1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL16960978 | 0.74 | NPC1 (0.35) | NPC1MAPTRAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |