Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950626 | 0.85 | NQO1 (0.41) | MEN1KMT2ATDP1MAPT | |
| SCHEMBL16957198 | 0.83 | ADRA2A (0.41) | ADRA2AADRA1AHTR2ASLC6A4KCNH2 | |
| SCHEMBL16958390 | 0.81 | CHRM2 (0.39) | ADRA2AADRA1ACYP2D6MEN1KMT2A | |
| SCHEMBL16961775 | 0.81 | ADRA1A (0.54) | ADRA2AADRA1AHTR2ACYP2D6MEN1 | |
| SCHEMBL16960094 | 0.80 | ADRA2A (0.38) | ADRA2AADRA1ACYP2D6MEN1KMT2A | |
| SCHEMBL16953982 | 0.79 | HTR2A (0.44) | ADRA2AADRA1AHTR2ASLC6A4KCNH2 | |
| SCHEMBL16951739 | 0.79 | ADRA2A (0.37) | ADRA2AADRA1ACYP2D6MEN1KMT2A | |
| SCHEMBL16950424 | 0.77 | ALKBH3 (0.35) | HTR2ASLC6A4KCNH2MEN1KMT2A | |
| SCHEMBL16960169 | 0.77 | TP53 (0.39) | MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL16954799 | 0.77 | HTR2A (0.35) | HTR2ASLC6A4KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |