Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954707 | 0.82 | TPMT (0.43) | SMN1; SMN2HDAC2TSHRMAPTHSD17B10 | |
| SCHEMBL17064144 | 0.79 | CYP3A4 (0.43) | PARP1CYP3A4SMN1; SMN2TSHRPOLB | |
| SCHEMBL5174897 | 0.78 | DHODH (0.50) | PARP1CYP3A4SMN1; SMN2TSHRPOLB | |
| SCHEMBL16960960 | 0.77 | PARP1 (0.46) | PARP1CYP3A4SMN1; SMN2HDAC2TSHR | |
| SCHEMBL16961939 | 0.77 | PARP1 (0.46) | PARP1CYP3A4SMN1; SMN2HDAC2TSHR | |
| SCHEMBL16951541 | 0.77 | PARP1 (0.46) | PARP1CYP3A4SMN1; SMN2TSHRPOLB | |
| SCHEMBL16958282 | 0.77 | CA1 (0.44) | TSHRPOLBHSD17B10TDP1L3MBTL1 | |
| SCHEMBL16955676 | 0.74 | BPTF (0.33) | PARP1CYP3A4SMN1; SMN2TSHRBPTF | |
| SCHEMBL16960433 | 0.73 | ALDH1A1 (0.42) | TSHRTDP1 | |
| SCHEMBL16953148 | 0.73 | ALDH1A1 (0.42) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |