Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16581118 | 0.81 | RAB9A (0.40) | RAB9ATPMTHCAR1SMN1; SMN2MEN1 | |
| SCHEMBL5048829 | 0.79 | PARP1 (0.60) | PARP1TPMTADRA1DMAP4K4HCAR1 | |
| SCHEMBL349820 | 0.79 | PARP1 (0.60) | PARP1RAB9ATPMTADRA1DMAP4K4 | |
| SCHEMBL5174897 | 0.78 | DHODH (0.50) | PARP1TPMTMKNK1MKNK2CYP3A4 | |
| SCHEMBL16961939 | 0.77 | PARP1 (0.46) | PARP1CYP3A4SMN1; SMN2POLBMEN1 | |
| SCHEMBL16962552 | 0.77 | PARP1 (0.33) | PARP1CYP3A4SMN1; SMN2POLBMAPT | |
| SCHEMBL16960960 | 0.77 | PARP1 (0.46) | PARP1HCAR1CYP3A4SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL4371939 | 0.77 | PARP1 (0.58) | PARP1RAB9ATPMTADRA1DMAP4K4 | |
| SCHEMBL16953741 | 0.76 | RAB9A (0.34) | RAB9ATPMT | |
| SCHEMBL14060424 | 0.74 | PARP1 (0.56) | PARP1RAB9ATPMTADRA1DMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024052701-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |