Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957892 | 0.85 | CTSL (0.35) | GABRA1GABRB2DAOIAPP | |
| SCHEMBL16961225 | 0.82 | SIRT2 (0.36) | ERN1PDK2 | |
| SCHEMBL1619349 | 0.82 | ERN1 (0.44) | GABRA1GABRB2KAT6AERN1MEN1 | |
| SCHEMBL16950364 | 0.80 | GABRA1 (0.40) | GABRA1GABRB2KAT6AERN1DAO | |
| SCHEMBL22306130 | 0.78 | GABRA1 (0.55) | GABRA1GABRB2KAT6ADAOMEN1 | |
| SCHEMBL16958549 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2DAOMAPTHTT | |
| SCHEMBL16960918 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2DAOIAPP | |
| SCHEMBL16950740 | 0.76 | GABRA1 (0.45) | GABRA1GABRB2LMNASMN1; SMN2PDK2 | |
| SCHEMBL16953361 | 0.76 | GABRA1 (0.61) | GABRA1GABRB2DAOIAPP | |
| SCHEMBL16955436 | 0.76 | GABRA1 (0.45) | GABRA1GABRB2LMNASMN1; SMN2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |