Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | FOS | P01100 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446308 | 0.82 | MAOB (0.62) | SMN1; SMN2ALOX5PTGS1PTGS2BCHE | |
| SCHEMBL5477544 | 0.76 | CYP1A2 (0.67) | KDM4EALDH1A1SMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL2949409 | 0.76 | CYP1A2 (0.67) | KDM4EALDH1A1SMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL14614293 | 0.75 | TLR4 (0.57) | KDM4EALDH1A1SMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL28377653 | 0.74 | MAOA (0.55) | KDM4EALDH1A1SMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL6320363 | 0.74 | MAOB (0.62) | SMN1; SMN2ALOX5PTGS1PTGS2BCHE | |
| SCHEMBL6318820 | 0.74 | MAOB (0.62) | SMN1; SMN2ALOX5PTGS1PTGS2BCHE | |
| SCHEMBL5479748 | 0.73 | NPSR1 (0.65) | ALOX5PTGS1PTGS2APPMAOB | |
| SCHEMBL16899699 | 0.73 | HSD17B3 (0.67) | ALDH1A1ALOX5PTGS1PTGS2PKM | |
| SCHEMBL481195 | 0.73 | HSD17B3 (0.67) | ALDH1A1ALOX5PTGS1PTGS2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900655-A1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-08-05 | — | — | EP | disclosed |