Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10183724 | 0.82 | LRRK2 (0.36) | LRRK2CYP1A2PDE2AKAT2BBRD9 | |
| SCHEMBL21241219 | 0.77 | LRRK2 (0.45) | LRRK2CYP1A2TRPA1HSD11B1P2RX7 | |
| SCHEMBL24483790 | 0.77 | CYP11B2 (0.45) | LRRK2CYP1A2TRPA1HSD11B1CYP11B2 | |
| SCHEMBL21720900 | 0.77 | LRRK2 (0.33) | LRRK2CYP1A2MEN1KMT2A | |
| SCHEMBL30231014 | 0.76 | TRPA1 (0.37) | LRRK2CYP1A2TRPA1HSD11B1CYP11B2 | |
| SCHEMBL31239670 | 0.76 | TRPA1 (0.37) | LRRK2CYP1A2TRPA1HSD11B1P2RX7 | |
| Ammonia Solution, Strong SCHEMBL29243357 | 0.76 | LRRK2 (0.44) | LRRK2CYP1A2TRPA1HSD11B1P2RX7 | |
| SCHEMBL22952638 | 0.74 | CYP11B2 (0.39) | LRRK2CYP1A2TRPA1HSD11B1P2RX7 | |
| SCHEMBL31239649 | 0.72 | TRPA1 (0.36) | LRRK2CYP1A2TRPA1HSD11B1P2RX7 | |
| SCHEMBL23082929 | 0.72 | TRPA1 (0.39) | LRRK2CYP1A2TRPA1HSD11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611165-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |
| EP-2900655-A1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-08-05 | — | — | EP | disclosed |