SCHEMBL16965114

SCHEMBL16965114

CCN(CC)C(=O)Oc1ccc(Cl)cc1OC(=O)N(CC)CC

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 6/20 0.57
▸ TSHR P16473 2/20 0.57
▸ SMN1; SMN2 Q16637 4/20 0.55
▸ MEN1 O00255 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ L3MBTL1 Q9Y468 3/20 0.53
▸ NPC1 O15118 2/20 0.50
▸ RAB9A P51151 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ HPGD P15428 1/20 0.50
▸ MAPT P10636 1/20 0.48
▸ HSD17B10 Q99714 2/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728538 1.00 LMNA (0.57) LMNATSHRSMN1; SMN2MEN1KMT2A
SCHEMBL13342902 0.87 LMNA (0.55) LMNATSHRSMN1; SMN2MEN1KMT2A
SCHEMBL22372573 0.86 LMNA (0.54) LMNATSHRSMN1; SMN2MEN1KMT2A
SCHEMBL29728539 0.81 LMNA (0.57) LMNATSHRSMN1; SMN2KMT2ANPC1
SCHEMBL17092986 0.81 LMNA (0.57) LMNATSHRSMN1; SMN2KMT2ANPC1
SCHEMBL29728640 0.78 HSD17B10 (0.70) LMNATSHRSMN1; SMN2MEN1KMT2A
SCHEMBL16965616 0.78 HSD17B10 (0.70) LMNATSHRSMN1; SMN2MEN1KMT2A
SCHEMBL16555608 0.78 KMT2A (0.44) LMNATSHRSMN1; SMN2MEN1KMT2A
SCHEMBL16555915 0.78 KMT2A (0.44) LMNATSHRSMN1; SMN2MEN1KMT2A
SCHEMBL22208756 0.78 LMNA (0.59) LMNATSHRSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286504-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2025-04-29 — — US disclosed
EP-4031588-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2023-09-20 — — EP disclosed
US-20220298272-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-09-22 — — US disclosed
WO-2021052733-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2021-03-25 — — WO disclosed
US-9670298-B2 Magnesium dichloride-ethanol adducts and catalyst component obtained therefrom BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2017-06-06 — — US disclosed
EP-2900706-B1 MAGNESIUM DICHLORIDE-ETHANOL ADDUCTS AND CATALYST COMPONENTS OBTAINED THEREFROM BASELL POLIOLEFINE ITALIA SRL (IT) 2016-12-14 — — EP disclosed
US-20150266981-A1 MAGNESIUM DICHLORIDE-ETHANOL ADDUCTS AND CATALYST COMPONENT OBTAINED THEREFROM BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2015-09-24 — — US disclosed
EP-2900706-A1 MAGNESIUM DICHLORIDE-ETHANOL ADDUCTS AND CATALYST COMPONENTS OBTAINED THEREFROM Basell Poliolefine Italia S.r.l. (IT) 2015-08-05 — — EP disclosed
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