SCHEMBL17092986

SCHEMBL17092986

CN(C)C(=O)Oc1ccc(Cl)cc1OC(=O)N(C)C

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.57
▸ SMN1; SMN2 Q16637 1/20 0.57
▸ RAB9A P51151 2/20 0.54
▸ NPC1 O15118 1/20 0.54
▸ TSHR P16473 1/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ FAAH O00519 1/20 0.54
▸ NCEH1 Q6PIU2 7/20 0.51
▸ KDM4E B2RXH2 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728539 1.00 LMNA (0.57) LMNASMN1; SMN2RAB9ANPC1TSHR
SCHEMBL13342911 0.86 LMNA (0.55) LMNASMN1; SMN2RAB9ANPC1TSHR
SCHEMBL29517939 0.84 LMNA (0.54) LMNASMN1; SMN2RAB9ANPC1TSHR
SCHEMBL22372583 0.84 LMNA (0.54) LMNASMN1; SMN2RAB9ANPC1TSHR
SCHEMBL11713526 0.82 LMNA (0.51) LMNASMN1; SMN2RAB9ANPC1TSHR
SCHEMBL29728538 0.81 LMNA (0.57) LMNASMN1; SMN2RAB9ANPC1TSHR
SCHEMBL16965114 0.81 LMNA (0.57) LMNASMN1; SMN2RAB9ANPC1TSHR
SCHEMBL16965282 0.81 BCHE (0.44) LMNASMN1; SMN2TSHRKMT2AALDH1A1
SCHEMBL29728595 0.81 BCHE (0.44) LMNASMN1; SMN2TSHRKMT2AALDH1A1
SCHEMBL11338058 0.79 KDM4E (0.58) LMNASMN1; SMN2RAB9ANPC1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12286504-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2025-04-29 — — US disclosed
EP-4031588-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2023-09-20 — — EP disclosed
US-20220298272-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-09-22 — — US disclosed
WO-2021052733-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2021-03-25 — — WO disclosed
US-9670298-B2 Magnesium dichloride-ethanol adducts and catalyst component obtained therefrom BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2017-06-06 — — US disclosed
US-20150266981-A1 MAGNESIUM DICHLORIDE-ETHANOL ADDUCTS AND CATALYST COMPONENT OBTAINED THEREFROM BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2015-09-24 — — US disclosed
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