Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL886358 | 0.89 | INSR (0.69) | INSRMET | |
| SCHEMBL16966220 | 0.78 | MET (0.60) | INSRMET | |
| SCHEMBL885980 | 0.78 | INSR (1.00) | INSRMET | |
| SCHEMBL16965957 | 0.78 | MET (0.46) | INSRMET | |
| SCHEMBL16965931 | 0.75 | INSR (0.70) | INSRMET | |
| SCHEMBL16966242 | 0.74 | INSR (0.64) | INSRMET | |
| SCHEMBL16966038 | 0.74 | MET (0.61) | INSRMET | |
| SCHEMBL16965930 | 0.74 | INSR (0.72) | INSRMET | |
| SCHEMBL886342 | 0.74 | INSR (1.00) | INSRMET | |
| SCHEMBL16965961 | 0.73 | MET (0.44) | INSRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684874-B1 | Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and C-met inhibitors | CEPHALON INC (US) | 2017-05-17 | — | — | EP | claimed |
| EP-2222647-B1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | CEPHALON INC (US) | 2015-08-05 | — | — | EP | claimed |