Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.37 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.37 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119831 | 0.86 | AURKA (0.51) | AURKAPDPK1AURKBEIF2AK4 | |
| SCHEMBL3124312 | 0.82 | CCNC (0.46) | CCNCCDK8LMNAGAA | |
| SCHEMBL16966456 | 0.81 | KDM4E (0.34) | CCNCCDK8AURKAPDPK1AURKB | |
| SCHEMBL16966457 | 0.80 | AURKA (0.46) | CCNCCDK8AURKAPDPK1AURKB | |
| SCHEMBL1318649 | 0.78 | AURKA (0.35) | CCNCCDK8AURKAPDPK1AURKB | |
| SCHEMBL1318713 | 0.78 | AURKA (0.43) | CCNCCDK8AURKAPDPK1AURKB | |
| SCHEMBL16966480 | 0.77 | PDPK1 (0.42) | CCNCCDK8AURKAPDPK1AURKB | |
| SCHEMBL16966439 | 0.77 | AURKA (0.38) | CCNCCDK8AURKAPDPK1AURKB | |
| SCHEMBL1318652 | 0.75 | AURKA (0.36) | CCNCCDK8AURKAPDPK1AURKB | |
| SCHEMBL16966468 | 0.75 | AURKA (0.41) | AURKAPDPK1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-B1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2015-08-05 | — | — | EP | disclosed |