SCHEMBL1696681

SCHEMBL1696681

NC([C]=O)Cc1ccsc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TAAR1 Q96RJ0 1/20 0.44
▸ SLC1A3 P43003 2/20 0.41
▸ SLC1A2 P43004 2/20 0.41
▸ SLC1A1 P43005 2/20 0.41
▸ DRD2 P14416 2/20 0.41
▸ DRD3 P35462 2/20 0.41
▸ DPP4 P27487 2/20 0.40
▸ DPP8 Q6V1X1 1/20 0.40
▸ DPP9 Q86TI2 1/20 0.40
▸ SLC6A2 P23975 1/20 0.37
▸ SLC6A3 Q01959 1/20 0.37
▸ MME P08473 3/20 0.36
▸ MEN1 O00255 1/20 0.34
▸ KDM4A O75164 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ KDM4C Q9H3R0 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1696682 1.00 TAAR1 (0.44) TAAR1SLC1A3SLC1A2SLC1A1DRD2
SCHEMBL19812643 0.75 TAAR1 (0.47) TAAR1SLC1A3SLC1A2SLC1A1DRD2
SCHEMBL28905950 0.74 — —
SCHEMBL14478277 0.74 — —
SCHEMBL4135682 0.74 — —
SCHEMBL1696684 0.73 SLC1A3 (0.45) TAAR1SLC1A3SLC1A2SLC1A1DRD2
SCHEMBL13962958 0.73 SLC1A3 (0.45) TAAR1SLC1A3SLC1A2SLC1A1DRD2
Hydrochloric Acid SCHEMBL9433817 0.72 TAAR1 (0.48) TAAR1SLC6A2SLC6A3
SCHEMBL160633 0.72 SLC7A5 (0.58) SLC1A3SLC1A2SLC1A1DRD3DPP4
SCHEMBL5257074 0.72 DPP4 (0.48) TAAR1SLC1A3SLC1A2SLC1A1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2585482-B1 GLUCAGON ANALOGUES ZEALAND PHARMA AS (DK) 2019-03-27 — — EP claimed
US-20150376257-A1 GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2015-12-31 — — US claimed
US-20130157929-A1 GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2013-06-20 — — US claimed
EP-2585482-A1 GLUCAGON ANALOGUES Zealand Pharma A/S (DK) 2013-05-01 — — EP claimed
WO-2011160633-A1 GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2011-12-29 — — WO claimed
EP-2585482-B1 GLUCAGON ANALOGUES ZEALAND PHARMA AS (DK) 2019-03-27 — — EP disclosed
EP-2525809-B1 GLUCAGON-GLP1 DUAL AGONISTS FOR USE IN THE TREATMENT OF CARDIAC CONDITIONS ZEALAND PHARMA AS (DK) 2016-08-03 — — EP disclosed
US-20150376257-A1 GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2015-12-31 — — US disclosed
US-9169310-B2 Glucagon analogues ZEALAND PHARMA A/S (DK) 2015-10-27 — — US disclosed
US-20130157929-A1 GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2013-06-20 — — US disclosed
US-20130157953-A1 TREATMENT OF CARDIAC CONDITIONS ZEALAND PHARMA A/S (DK) 2013-06-20 — — US disclosed
EP-2585482-A1 GLUCAGON ANALOGUES Zealand Pharma A/S (DK) 2013-05-01 — — EP disclosed
WO-2011160633-A1 GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2011-12-29 — — WO disclosed
WO-2011088837-A1 TREATMENT OF CARDIAC CONDITIONS ZEALAND PHARMA A/S (DK) 2011-07-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150376257-A1 GLUCAGON ANALOGUES GLP1R, GCGR, GIPR TAAR1 1070/4885SLC1A3 2769/4885SLC1A2 4014/4885
US-20130157953-A1 TREATMENT OF CARDIAC CONDITIONS GLP1R, GCGR, TNNT2 TAAR1 1609/4885SLC1A3 619/4885SLC1A2 583/4885
US-20130157929-A1 GLUCAGON ANALOGUES GLP1R, GCGR, GIPR TAAR1 1070/4885SLC1A3 2769/4885SLC1A2 4014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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