Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1696684 | 1.00 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1TAAR1DPP4 | |
| SCHEMBL28379986 | 0.81 | TAAR1 (0.44) | SLC1A3SLC1A2SLC1A1TAAR1DPP4 | |
| SCHEMBL19812644 | 0.75 | TAAR1 (0.47) | SLC1A3SLC1A2SLC1A1TAAR1DPP4 | |
| SCHEMBL4135682 | 0.74 | — | — | |
| SCHEMBL28905950 | 0.74 | — | — | |
| SCHEMBL14478277 | 0.74 | — | — | |
| SCHEMBL1696681 | 0.73 | TAAR1 (0.44) | SLC1A3SLC1A2SLC1A1TAAR1DPP4 | |
| SCHEMBL1696682 | 0.73 | TAAR1 (0.44) | SLC1A3SLC1A2SLC1A1TAAR1DPP4 | |
| SCHEMBL15203049 | 0.73 | OPRM1 (0.40) | SLC1A3SLC1A2SLC1A1TAAR1MME | |
| SCHEMBL22086282 | 0.73 | OPRM1 (0.40) | SLC1A3SLC1A2SLC1A1TAAR1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482379-B2 | Propenoyl hydrazides | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-01-27 | — | — | US | disclosed |