SCHEMBL1696705

SCHEMBL1696705

N[C@H](C=O)Cc1ccco1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
SLC1A1 P43005 1/20 0.44
ALOX5 P09917 1/20 0.43
CHRM2 P08172 1/20 0.38
ALDH1A1 P00352 4/20 0.38
USP2 O75604 2/20 0.36
GAA P10253 2/20 0.36
HPGD P15428 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAOB P27338 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 2/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10664022 1.00 SLC1A3 (0.44) SLC1A3SLC1A2SLC1A1ALOX5CHRM2
SCHEMBL10946101 0.81 ALDH1A1 (0.43) SLC1A3SLC1A2SLC1A1ALOX5CHRM2
SCHEMBL28585127 0.78 ALDH1A1 (0.39) SLC1A3SLC1A2SLC1A1ALOX5CHRM2
SCHEMBL29175498 0.77
SCHEMBL5311463 0.77 RAB9A (0.41) SLC1A3SLC1A2SLC1A1ALOX5CHRM2
SCHEMBL9523165 0.77 ALDH1A1 (0.41) SLC1A3SLC1A2SLC1A1ALOX5CHRM2
SCHEMBL2398239 0.74 MIF (0.45) SLC1A3SLC1A2SLC1A1ALOX5ALDH1A1
SCHEMBL14478276 0.74
SCHEMBL13692285 0.74
SCHEMBL2022682 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2585482-B1 GLUCAGON ANALOGUES ZEALAND PHARMA AS (DK) 2019-03-27 EP claimed
US-20150376257-A1 GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2015-12-31 US claimed
US-20130157929-A1 GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2013-06-20 US claimed
EP-2585482-A1 GLUCAGON ANALOGUES Zealand Pharma A/S (DK) 2013-05-01 EP claimed
WO-2011160633-A1 GLUCAGON ANALOGUES ZEALAND PHARMA A/S (DK) 2011-12-29 WO claimed
US-20060194737-A1 Hepta-, octa-and nonapeptides having antiangiogenic activity HAVIV FORTUNA 2006-08-31 US claimed
US-7067490-B2 Hepta-, Octa-and nonapeptides having antiangiogenic activity ABBOTT LABORATORIES (US) 2006-06-27 US claimed
EP-1451210-A2 HEPTA-, OCTA- AND NONAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY Abbott Laboratories (US) 2004-09-01 EP claimed
EP-1421107-A1 PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY Abbott Laboratories (US) 2004-05-26 EP claimed
US-20030125259-A1 Octa- and nonapeptides having antiangiogenic activity ABBOTT LABORATORIES 2003-07-03 US claimed
US-20030109455-A1 HEPTA-, OCTA-and nonapeptides having antiangiogenic activity ABBVIE INC. 2003-06-12 US claimed
US-20030096758-A1 HEPTA-, OCTA- and nonapeptides having antiangiogenic activity ABBOTT LABORATORIES 2003-05-22 US claimed
WO-2003037268-A2 HEPTA-, OCTA- AND NONAPEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LABORATORIES (US) 2003-05-08 WO claimed
US-20030050246-A1 Peptides having antiangiogenic activity ABBOTT LABORATORIES 2003-03-13 US claimed
US-20030045477-A1 Peptides having antiangiogenic activity ABBOTT LABORATORIES 2003-03-06 US claimed
WO-2003011896-A1 PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LABORATORIES (US) 2003-02-13 WO claimed
EP-2585482-B1 GLUCAGON ANALOGUES ZEALAND PHARMA AS (DK) 2019-03-27 EP disclosed
EP-2525809-B1 GLUCAGON-GLP1 DUAL AGONISTS FOR USE IN THE TREATMENT OF CARDIAC CONDITIONS ZEALAND PHARMA AS (DK) 2016-08-03 EP disclosed
US-20030045477-A1 Peptides having antiangiogenic activity ABBOTT LABORATORIES 2003-03-06 US disclosed
WO-2003011896-A1 PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY ABBOTT LABORATORIES (US) 2003-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150376257-A1 GLUCAGON ANALOGUES GLP1R, GCGR, GIPR SLC1A3 2769/4885SLC1A2 4014/4885SLC1A1 3560/4885
US-20130157929-A1 GLUCAGON ANALOGUES GLP1R, GCGR, GIPR SLC1A3 2769/4885SLC1A2 4014/4885SLC1A1 3560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.