⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8757762 | 0.88 | CHRM2 (0.34) | — | |
| SCHEMBL620009 | 0.72 | — | — | |
| SCHEMBL3537893 | 0.71 | — | — | |
| SCHEMBL447925 | 0.71 | — | — | |
| SCHEMBL5228195 | 0.70 | — | — | |
| SCHEMBL2053024 | 0.69 | HTR3A (0.33) | — | |
| SCHEMBL9326124 | 0.68 | — | — | |
| SCHEMBL3044885 | 0.68 | — | — | |
| SCHEMBL361683 | 0.68 | — | — | |
| SCHEMBL6921607 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 926 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132278-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | UNIVERSITÄT REGENSBURG (DE) | 2024-06-27 | — | — | WO | claimed |
| EP-4389223-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | Universität Regensburg (DE) | 2024-06-26 | — | — | EP | claimed |
| CN-117567392-A | Pterocarpus stilbene paeonol acetic acid compound, and preparation method and medical application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-110809576-B | FGFR kinase inhibitor and pharmaceutical use | 奥克兰联合服务有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-114466913-A | Dihydroquinoline photochromic compounds | 光学转变有限公司 | 2022-05-10 | — | — | CN | claimed |
| US-11192890-B2 | FGFR kinase inhibitors and pharmaceutical uses | AUCKLAND UNISERVICES LIMITED (NZ) | 2021-12-07 | — | — | US | claimed |
| US-20210179600-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS INHIBITORS OF ASK1 | Hepagene Therapeutics (HK) Limited (HK) | 2021-06-17 | — | — | US | claimed |
| EP-3323813-B1 | HISTONE ACETYLTRANSFERASE MODULATORS AND USES THEREOF | UNIV COLUMBIA (US) | 2020-08-26 | — | — | EP | claimed |
| CN-106008552-B | Benzo [ e ] pyrazolo [1,5-c ] [1,3] oxazine compound and application thereof | 南京圣和药业股份有限公司 | 2020-08-21 | — | — | CN | claimed |
| US-20200216432-A1 | SULFONAMIDE DERIVATIVES AS STAT3 INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | KING'S COLLEGE LONDON (GB) | 2020-07-09 | — | — | US | claimed |
| US-4374779-A | Nitrosoamino-actonitriles | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-02-22 | — | — | US | claimed |
| US-4343885-A | PHOTORESISTS | DYNACHEM CORPORATION (US) | 1982-08-10 | — | — | US | claimed |
| US-4324897-A | 1,2,3 Oxadiazolium salts | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-04-13 | — | — | US | claimed |
| EP-0005380-B1 | PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER | Dynachem Corporation (US) | 1982-01-06 | — | — | EP | claimed |
| EP-0005379-B1 | PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS | Dynachem Corporation (US) | 1981-12-23 | — | — | EP | claimed |
| US-4279819-A | GASTROINTESTINAL DISORDERS | ALLEN & HANBURYS LTD. (GB) | 1981-07-21 | — | — | US | claimed |
| US-4233312-A | Esters of indole-1-acetic acid and analgesic use thereof | ROUSSEL UCLAF (FR) | 1980-11-11 | — | — | US | claimed |
| EP-0005299-A1 | Substituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, process for the preparation thereof, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-11-14 | — | — | EP | claimed |
| EP-0005380-A2 | Phototropic photosensitive compositions containing a fluoran colorformer | Dynachem Corporation (US) | 1979-11-14 | — | — | EP | claimed |
| EP-0005379-A2 | Photosensitive compositions containing carbonylic halides as activators | Dynachem Corporation (US) | 1979-11-14 | — | — | EP | claimed |