⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533333 | 0.88 | — | — | |
| SCHEMBL3537893 | 0.82 | — | — | |
| SCHEMBL3044885 | 0.78 | — | — | |
| SCHEMBL9326124 | 0.78 | — | — | |
| SCHEMBL7344795 | 0.76 | GLA (0.35) | — | |
| SCHEMBL6961881 | 0.75 | KEAP1 (0.32) | — | |
| SCHEMBL3253791 | 0.75 | MEN1 (0.35) | — | |
| SCHEMBL11599897 | 0.74 | POLB (0.52) | — | |
| SCHEMBL254649 | 0.74 | GNAO1 (0.38) | — | |
| SCHEMBL1476931 | 0.74 | MEN1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125997-A | Pterocarpus stilbene paeonol chalcone amide derivative, preparation method and medical application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | claimed |
| US-20230310428-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-10-05 | — | — | US | claimed |
| US-20230212147-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-07-06 | — | — | US | claimed |
| EP-4166553-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-04-19 | — | — | EP | claimed |
| WO-2023011610-A1 | BENZODIOXANE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 南京红云生物科技有限公司 | 2023-02-09 | — | — | WO | claimed |
| WO-2021254464-A1 | SUBSTITUTED QUINAZOLINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 南京红云生物科技有限公司 | 2021-12-23 | — | — | WO | claimed |
| WO-2021238827-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | 南京红云生物科技有限公司 | 2021-12-02 | — | — | WO | claimed |
| EP-3290420-B1 | PYRIMIDINE PYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES THEREOF | UNIV XIAMEN (CN) | 2020-12-09 | — | — | EP | claimed |
| CN-109593064-B | Dithiocarbamate compounds as BTK inhibitors | 北京博远精准医疗科技有限公司 | 2020-08-11 | — | — | CN | claimed |
| CN-109503548-B | Butylphthalide derivative and preparation method and application thereof | 江南大学 | 2020-08-04 | — | — | CN | claimed |
| US-5916899-A | SOLID PHASE SYNTHESIS, REACTING PROTECTED AMINO ACID WITH SOLID SUPPORT; FORMING IMINE BY REACTION WITH ALDEHYDE, CYCLIZATION WITH ANHYDRIDE, CLEAVAGE AND DEPROTECTION. | TREGA BIOSCIENCES, INC. (US) | 1999-06-29 | — | — | US | claimed |
| US-5874443-A | BIOSYNTHESIS | TREGA BIOSCIENCES, INC. (US) | 1999-02-23 | — | — | US | claimed |
| EP-0863877-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | claimed |
| US-4675320-A | INHIBIT GROWTH OF MICROORGANISMS | RIKER LABORATORIES, INC. (US) | 1987-06-23 | — | — | US | claimed |
| EP-0140062-B1 | PERFLUOROALKYL ANTHRANILATES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS DIRT-REPELLING AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-06 | — | — | EP | claimed |
| US-4587338-A | SOIL REPELLENT FINISHES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-05-06 | — | — | US | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| EP-0140062-A1 | Perfluoroalkyl anthranilates, processes for their preparation and their use as dirt-repelling agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-08 | — | — | EP | claimed |
| EP-0000479-B1 | SUBSTITUTED 1-PIPERAZINYL-4H-S-TRIAZOLO (3,4-C)THIENO(2,3-E)1,4-DIAZEPINES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | C.H. BOEHRINGER SOHN (DE) | 1981-01-07 | — | — | EP | claimed |