SCHEMBL1697134

SCHEMBL1697134

CC(C)(C)O[P]OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331465 0.67
SCHEMBL7592494 0.67
SCHEMBL17958831 0.65
Tert-Butyl Hydroperoxide SCHEMBL3026366 0.57
Tert-Butyl Hydroperoxide SCHEMBL6896488 0.57 ALDH1A1 (0.39) ALDH1A1TSHRTDP1
Tert-Butyl Hydroperoxide SCHEMBL10352877 0.57 ALDH1A1 (0.39) ALDH1A1TSHRTDP1
Tert-Butyl Hydroperoxide SCHEMBL11312020 0.57
Tert-Butyl Hydroperoxide SCHEMBL3198636 0.57 ALDH1A1 (0.39) ALDH1A1TSHRTDP1
Tert-Butyl Hydroperoxide SCHEMBL20163 0.57
SCHEMBL503396 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114105860-A Catalytic asymmetric synthesis method and application of chiral oxindole spiro-analogue 重庆大学 2022-03-01 CN disclosed
EP-2595630-A1 USE OF A2B ADENOSINE RECEPTOR ANTAGONISTS FOR TREATING PULMONARY HYPERTENSION Gilead Sciences, Inc. (US) 2013-05-29 EP disclosed
WO-2012003220-A1 USE OF A2B ADENOSINE RECEPTOR ANTAGONISTS FOR TREATING PULMONARY HYPERTENSION GILEAD SCIENCES, INC. (US) 2012-01-05 WO disclosed